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Candidalysin(cas:1906866-53-2);念珠菌素; SIIGIIMGILGNIPQVIQIIMSIVKAFKGNK
α 螺旋结构:通过分子内氢键形成 α 螺旋,其疏水区与宿主细胞膜相互作用,促进膜穿孔(Moyes et al., 2016)。 加工成熟:由白念珠菌 ECE1 基因编码的前体蛋白经 Kex2p 和 Kex1p 蛋白酶切割生成,释放成熟毒素(Moyes et al., 2016)。 作用机理及研究进展 膜破坏与细胞 ...
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