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2 天
靶向 CXCR4 和 S1P5:解锁自然杀伤细胞抗肿瘤潜力的新策略
在探究自然杀伤(NK)细胞抗肿瘤机制的征程中,研究人员聚焦 NK 细胞脱颗粒的内在调节因子。经刺激人原代血源性 NK 细胞并测序分析,发现 CXCR4 和 S1PR5 为关键负调控基因。这一成果为肿瘤微环境中增强 NK 细胞杀伤能力提供了新方向。 在人体的免疫系统中 ...
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