肿瘤-神经交互作用作为近年肿瘤研究的前沿领域，其探索逐步从中枢神经系统（CNS）向周围神经系统（PNS）延伸。现有研究表明，肿瘤细胞可通过外周神经元调控实现生存优势，但 既往研究多集中于胶质瘤等CNS肿瘤与神经元的互作，而对PNS-肿瘤特别是胃癌领域的解析仍存在着诸多空白 。

点击蓝字关注我们生理稳态下小胶质细胞就像“外科医生”对脑实质进行持续的免疫监视，为神经元提供营养支持，清除凋亡碎片并消除功能紊乱的突触。在免疫刺激下，小胶质细胞启动防御程序，呈现免疫激活状态，其特征是吞噬作用增加，受体、细胞因子、趋化因子和其他炎症相 ...

癌症严重威胁全球健康，胃癌（GC）、食管癌（EC）、卵巢癌（OC）预后差。AXL 作为潜在抗癌靶点，其抑制剂 gilteritinib 在实体肿瘤中的作用不明。研究人员探究其在 AXL 阳性的 EC、OC、GC 中的疗效，发现 gilteritinib 显著抑制肿瘤细胞生长、转移，为临床治疗提供新方向。

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