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乳腺癌干细胞中 B7-H3 转录调控机制的蛋白组学解析:开辟癌症治疗新 ...
研究人员针对此开展了乳腺癌 CSCs 中 B7-H3 转录机制的研究。他们利用 DNA 亲和纯化 - 质谱(DAP-MS)技术,发现 DDB1 等关键转录因子调控 B7-H3 表达,为癌症治疗提供了新方向。 在癌症的复杂世界里,免疫检查点分子 B7-H3(一种 I 型跨膜糖蛋白,属于 B7 超家族 ...
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