为解决颗粒暴露引发炎症疾病的机制问题,研究人员开展研究,揭示了AMPK-TFEB/TFE3-DNMT3A/DOT1L轴调控溶酶体酸化基因,JNK-AP-1 ...
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染色质是一种高度有序的结构,主要由 DNA 、 组蛋白 和 其他染色体相关蛋白 组成。其基本单位是核小体,每个核小体由两个拷贝的组蛋白H2A、H2B、H3和H4构成。组蛋白的N末端尾部经历多种 翻译后修饰(PTM) ,这些修饰在转录、复制和染色体维持等生物过程中 ...
Many of the cells in our bodies are quiescent, that is, temporarily not dividing. Under certain physiological conditions such as during tissue repair and maintenance, quiescent cells receive the ...
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