为探究调控蛋白和组蛋白尾巴存在时，调控 RNA 对 DNMT3A 的调控作用，研究人员开展了非编码 RNA 调控 DNMT3A 机制的研究。结果发现 Fos ecRNA 与 mRNA 相关，且调控 RNA 在多蛋白 - RNA 复合物中主导调节 DNMT3A 活性。该研究为理解表观遗传调控提供了新视角。 在生命的 ...

当马斯克在社交媒体上描绘"20年实现火星自给自足"的蓝图时，一份来自《自然通讯生物学》的研究报告正悄然揭示着更残酷的真相：在国际空间站接受体检的14名宇航员中，100%检测到血液干细胞DNA突变，其中85%的样本携带与白血病直接相关的DNMT3A基因 ...

Scientists compared blood from frequent, long-term donors to that of more seldom ones and saw some key genetic differences in ...

Use precise geolocation data. Actively scan device characteristics for identification. Store and/or access information on a ...

为解决颗粒暴露引发炎症疾病的机制问题，研究人员开展研究，揭示了AMPK-TFEB/TFE3-DNMT3A/DOT1L轴调控溶酶体酸化基因，JNK-AP-1 ...

Men who had given blood more than 100 times in their life were more likely to have blood cells carrying certain beneficial mutations, suggesting that donating blood promotes the growth of these cells ...

Giving blood regularly may not just be saving the lives of other people, it could also be improving your own blood's health ...

But when they looked closer, they noticed that the clones from frequent donors carried mutations distinct from those in the control group, particularly in a gene called DNMT3A (a common area of ...

“It suggests that, every blood donation, you’re going to have a burst of EPO in your system and this is going to favour the growth of cells with these DNMT3A mutations,” says Encab ...

Researchers have discovered genetic mutations in frequent blood donors that may promote the production of healthy cells ...