(F) Map of essential genes involved with cystine/cysteine metabolism. Upregulated genes in JIMT1 are highlighted in red and downregulated genes in JIMT1 are highlighted in blue. (G) Expression of ...

Glutathione, known as the 'master antioxidant', is praised for its benefits including detoxification, boosting immunity, ...

Sulfur is both crucial to life and a potential threat to health. While colonic sulfur metabolism mediated by eukaryotic cells is relatively well studied, much less is known about sulfur metabolism ...

Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP to synthesize ribonucleotides ...

Caspases are a class of cysteine-aspartyl proteases that are ... cells to activate a signal-transduction pathway that triggers the transcription of a diverse set of IFN-inducible genes that ...

Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...