The addition of β-adrenergic receptor antagonists to a medical regimen for heart failure that includes angiotensin-converting enzyme (ACE) inhibitors as background therapy has been associated ...

Basic science researchers at the Johns Hopkins University School of Medicine are advancing heart health research by finding ...

The melanocortin 1 receptor (MC1R) is abundantly expressed in the skin and leukocytes, where it regulates skin pigmentation and inflammatory responses. Recently, MC1R was also found in the heart, but ...

Beta3-adrenergic receptors (β3AR) have emerged as significant players in the management of heart failure (HF) and cardiac function. Traditionally, beta-adrenergic receptors have been associated ...

Blockages in coronary arteries cause sudden heart attacks, leading to heart muscle damage. In contrast, heart failure is a ...

Alpha-1 adrenergic receptors (α1-ARs) play a significant role in the regulation of cardiovascular function, particularly in conditions such as heart failure and myocardial infarction (MI).

The latter promotes phenotypic changes in these cells that are consistent with cardiac remodeling. The effects of ET are mediated through interaction with two classes of cell surface receptors.

Retinoic acid-related orphan receptor α (RORα) participates in various pathological and physiological cardiovascular processes. The current research aims to elucidate the roles and mechanisms of RORα ...

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults ...

Tagrisso was linked to higher cardiac risks in patients with EGFR-mutant NSCLC, including a four-fold rise in cardiac events ...