Summary. Doripenem, a member of the β-lactam class of antibiotics, is the newest addition to the carbapenems. It exhibits concentration-independent bactericidal activity against gram-positive ...

In this report, we will review recent pharmacokinetic (PK) and PK/pharmacodynamic (PD) findings for the most often used antibiotics against major GNB with acquired resistance to carbapenems.

Antimicrobial resistance happens when bacteria and other microbes that can cause infections gain the ability to resist ...

Antimicrobial resistance happens when bacteria and other microbes that can cause infections gain the ability to resist ...

Data from 34 surveillance laboratories in 11 districts from January 1 to December 31, 2023, collated and analysed by KARS-Net, forms the basis of the antibiogram report ...

Analysis of clinical isolates of E coli ST131 identified 18 different carbapenemase genes, which could limit treatment ...

The largest growth was detected near sink drains. These genes can confer resistance to carbapenem antibiotics, which are last-resort therapies for treating newborn sepsis. These findings are alarming.

The emergence of multi-drug resistance in bacterial pathogens poses a threat to human health. Carbapenem-resistant microorganisms, especially Acinetobacter baumannii, has emerged as a serious ...

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of ...