在人类着丝粒核心，alpha 卫星 HORs 是动粒与基因组结合的遗传底物，动粒与着丝粒核心的相互作用受多种 DNA 结合蛋白调节，包括序列特异性 DNA 结合蛋白 CENP-B 和组蛋白 H3 变体 CENP-A。成像和基因组研究表明，动粒结合仅局限于 alpha 卫星 HOR 阵列的一小部分 ...

Phosphorylation of this domain by Ipl1/Aurora B also aided the stability of assembled chaperone Scm3, CENP-A/Cse4 and centromeric DNA. These findings emphasize the importance of the N-terminal domain ...

发病时 RP、VC 改变、肿手和肢端青紫与 SSc 演变显著相关。VC 改变中，硬皮病样模式和非特异性改变均与演变相关。抗 CENP - B 和抗拓扑异构酶 I 等 SSc 特异性自身抗体可预测演变，抗 Ro/SSA 是 SSc 进展的保护因素。单因素分析确认相关因素，多因素分析因病例数少 ...

Berkshire Hathaway Inc., through its subsidiaries, engages in the insurance, freight rail transportation, and utility businesses worldwide. The company provides property, casualty, life, accident ...

THE WEEK’S MOST POPULAR CURRENT R&B/HIP-HOP SONGS ACROSS ALL GENRES, RANKED BY STREAMING ACTIVITY DATA BY ONLINE MUSIC SOURCES TRACKED BY LUMINATE, RADIO AIRPLAY AUDIENCE IMPRESSIONS AS MEASURED ...

hot r&b songs the week’s most popular current r&b songs across all genres, ranked by streaming activity data by online music sources tracked by luminate, radio airplay audience impressions as ...

What Is B-Cell Lymphoma? B-cell lymphoma is a cancer that forms in your white blood cells called lymphocytes. These cells are made by your lymphatic system, which plays an important role in immunity.

Welcome back to FTW’s Beverage of the Week series. Here, we mostly chronicle and review beers, but happily expand that scope to any beverage that pairs well with sports. Yes,even cookie dough ...