近日，国家生物信息中心（中国科学院北京基因组研究所）张维绮研究团队与中国科学院动物研究所刘光慧团队合作，在Science China Life Sciences在线发表题为“RIG-I-driven CDKN1A stabilization ...

多组学分析章节"CHD8 deficiency alters gene expression in Tregs"鉴定出Cdkn1a、Bhlhe40等关键基因表达上调，通路富集显示mTORC1、p53等信号异常激活。 "CHD8 regulates chromatin ...

▷ 该研究报告表示：衰老是一种内在的生物过程，其特征是系统性改变逐渐损害生理完整性，并且增加对与年龄相关的疾病的易感性，最终导致机体死亡。衰老的标志包括细胞衰老、基因组不稳定性、表观遗传改变、蛋白质稳态丧失、干细胞耗竭、慢性炎症和细胞间通讯改变。

2025年1月，国际权威杂志《时尚芭莎·印度》重磅发布专题报道《Why exosome therapy is 2025’s ‘It’ skincare trend（为什么外泌体疗法会成为2025年的护肤潮流）》，直指外泌体疗法将成为年度护肤新趋势。

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots? This is one of the questions that a team of researchers from Aarhus University ...

Over the past two decades, at least four major research programmes have formed in evo–devo, although there is extensive overlap among them. Figure 1: A morphodynamic model relating shape change ...

为探究 ZNF768 在体内的生理和病理作用，研究人员构建 ZNF768 敲除小鼠模型，发现其可抑制肺癌发生，为肿瘤治疗提供新靶点。 在生命的微观世界里，细胞增殖如同一场有序的交响乐，它是生物体生长、发育和维持正常功能的基础。然而，当这场交响乐失去控制，就会奏响疾病的 “悲歌”，癌症便是其中最沉重的音符。肿瘤蛋白 53（p53）作为 “基因组的守护者”，在细胞面临危机，如 DNA ...

Glioblastomas are the most prevalent primary brain tumors and are associated with a dramatically poor prognosis. Despite an intensive treatment approach, including maximal surgical tumor removal ...

Background: Stroke is the second leading cause of death and the third leading cause of disability worldwide, with ischemic stroke (IS) being the most prevalent. A substantial number of irreversible ...