图5 短IL-18促进癌细胞中Se 727上的STAT1磷酸化以动员NK细胞 6、短IL-18与CDK8互作激活STAT1 作者对肿瘤细胞上清液进行了质谱分析(图5g)以确定癌细胞上清中受短IL-18-STAT1轴调控的分子。结果显示,短IL-18显著增强了ISG15蛋白的分泌(图6a-b)。此外,由于短IL-18显著 ...
The physiological roles of these two kinases, CDK8 and CDK19, are currently rather poorly understood; although conserved in all eukaryotes, and among the most highly conserved kinases in vertebrates, ...
长期在中国工作的一些朝鲜工人最近得到了特别假期,允许外出给故乡寄包裹了。因此工人们为了买给家人的礼物要求管理干部支付代管的工资,可是遭到了拒绝引发了纠纷。 21日,中国当地消息人士对DailyNK表示:“在辽宁省大连的一家水产加工厂工作的工人中 ...
#Trump N Korea Trump says there's 'communication' with N.K. leader Kim U.S. President Donald Trump said Monday there is "communication" with North Korean leader Kim Jong-un while noting he will "do ...
This important study investigates the role of ATG6 in regulating NPR1, a key protein in the plant immune response. The authors present compelling evidence that ATG6 not only interacts with NPR1 in ...