FITC labeled anti-mouse CD45 mAb and PE labeled anti-mouse CD8a mAb were from Biolegend ... In summary, obesity promote the expression of PD-1 by up-regulating the glycolytic-mediated histone ...

We infected Nur77 mice with lymphocytic choriomeningitis virus (LCMV-Armstrong) to generate a robust memory compartment, where quiescent LCMV-specific memory CD8 + T cells could be readily tracked ...

JACKSON, Miss. (WLOX) - At the 2025 Mississippi Association of Broadcasters (MAB) awards Saturday night in Jackson, WLOX took home 31 Excellence in Broadcasting awards, 11 of those being first place.

沉默KLF2促使CD8 T细胞沿着不同的分化路径发展，引导它们远离杀伤性T细胞，进入一种称为衰竭的功能失调状态，这种状态会降低这些细胞对抗感染和 ...

Engineering Research Center of Applied Technology of Pharmacogenomics (Ministry of Education), Hunan Key Laboratory of Pharmacomicrobiomics, Department of Clinical Pharmacology, Xiangya Hospital, ...

This study reports valuable findings on the role of Layilin in the motility and suppressive capacity of clonal expanded regulatory T cells (Tregs) in the skin. Although the strength of the study is ...

图5 CPT1A水平与PD-1 mAb在黑色素瘤中的疗效相关 综上所述，本文从PD-1琥珀酰化的角度，阐明了线粒体代谢在肿瘤免疫中的作用。研究发现，提高琥珀酰辅酶A的水平可增强CD8+ T细胞介导的肿瘤消除。机制上，CPT1A作为关键的琥珀酰转移酶，可催化PD-L1第129位赖氨酸 ...

Cutting down on manufacturing costs when compared to monoclonal antibody (mAb) drugs, Imugene’s vaccines are also potentially safer ... This included strong and long-lasting induction of CD8 and CD4 T ...