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通过35色成像质谱流式寻找HIV与肠道免疫细胞的对话
免疫细胞亚群解析: 单核吞噬细胞:Axl+树突细胞(Axl+ CD45+ CD163+ CD303+)和Siglec-1+巨噬细胞(CD45+ CD163+ Siglec-1+)被鉴定为潜在HIV靶细胞。 T细胞动态:肠道归巢T细胞(CCR6+)、Th1(CXCR3+)、Th17(IL-17+)等亚群的空间分布与HIV感染区域高度相关。 组织结构关联 ...
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