此前研究发现，高血压的发生与多种因素相关，基因在其中起着重要作用，约 60% 的高血压风险变异可归因于遗传因素。MTHFR 基因编码的亚甲基四氢叶酸还原酶，对同型半胱氨酸（Hcy）和叶酸代谢至关重要。MTHFR C677T 多态性会使酶活性降低，导致 Hcy 水平升高，进而增加心血管疾病、中风等风险。然而，以往关于 MTHFR C677T 多态性、血清 Hcy 和高敏 C ...

Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory musculoskeletal disease associated with psoriasis, a chronic autoimmune skin disease affecting 2-3% of the world’s population and ...

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This report is based on two common genetic variants in the MTHFR gene, called C677T and A1298C, that can lead to small increases in homocysteine levels. If homocysteine is too high, it can ...

Lauren Neuenschwander on January 15, 2019: I have had 3 miscarriages around 9-10 weeks. I havent had any live births. Im 33 and my husband is 34. We just found out we BOTH have the c677t homozygous ...

心梗脑梗发生后，缺血组织中的自由基和炎症细胞因子会大量增加，导致组织进一步受损，这种现象被称作“再灌注损伤”。维生素B2可以通过减少自由基的产生和调节炎症反应，来减轻再灌注损伤的程度。动物实验已经表明，维生素B2预处理能够显著降低肝脏、大脑和心脏等器 ...

在国家级杂志发表学术论文十余篇，获市级科研成果二等奖二项。牵头的“MTHFR C677T基因多态性与慢性肺源性心脏病的相关性”于2018年6月荣获河南省科学技术成果证书、2019年6月荣获河南医学科技奖三等奖。多次被评为先进工作者、优秀共产党员。 平台声明 ...