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综述:X连锁凋亡抑制蛋白(XIAP)在肿瘤发展中的关键作用
推荐语:这篇综述系统阐述了X连锁凋亡抑制蛋白(XIAP)通过抑制caspases、激活核因子κB(NF-κB)等通路调控凋亡的双重途径(死亡受体与线粒体途径),其异常表达与肿瘤发生发展密切相关,为靶向治疗提供了新思路。 XIAP的结构与功能特性 X连锁凋亡抑制蛋白 ...
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