It was shown that arginine induced expression of Bcl-2 and Bcl-xL, while rReg4 upregulated Bcl-2 and Bcl-xL expression by activating the EGFR/Akt pathway. The upregulation of Bcl-xL correlated ...

[66,67] Lung tumor cells displaying early-resistance to EGFR TKIs exhibited dependence on MET-independent activation of STAT3-Bcl2/Bcl-XL survival pathway, suggesting that this could be an early ...

Both transcriptomic analysis and network analysis revealed the JAK/STAT signaling pathway as a key mechanism. Ginsenoside Rh2 inhibited tumor growth in TNBC mice and reduced the expression of IL- 6, ...

although alternative methods of targeting these pathways may be effective. MEK inhibitors form the backbone of multiple regimens entering clinical trials and are being combined with BCL-XL ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

SIAIS361034作为一种新型的靶向BCL-XL的PROTAC药物，无论是单独使用还是与PTX联合使用，在肿瘤治疗方面都展现出了巨大的潜力。 在癌症研究与治疗的 ...

BCL Industries Limited is an India-based agro-processing manufacturing company with diverse businesses and vertical integrations. Its segments include Oil & Vanaspati, Distillery and Real Estate ...

BCL Industries Ltd., incorporated in the year 1976, is a Small Cap company (having a market cap of Rs 1,410.88 Crore) operating in Agro Processing sector. BCL Industries Ltd. key Products/Revenue ...

BCL Enterprises Ltd., incorporated in the year 1985, is a Small Cap company (having a market cap of Rs 10.73 Crore) operating in Financial Services sector. BCL Enterprises Ltd. key Products/Revenue ...

Three very important feasts and the pattern of the Tabernacle and the Ark of the Covenant — all symbolic of Christ and His relationship with believers today. And let them make Me a Sanctuary; that I ...