The exosomal Argonaute 2 (AGO2) protein forms a complex with siRNAs, which is essential for siRNA-mediated gene silencing in bacteria. Even though the delivered siRNA was designed for possessing ...
南京大学研究团队通过外泌体介导的siRNA递送技术成功将MRSA转化为对甲氧西林敏感的细菌,为治疗多重耐药细菌感染提供新策略。该技术展示了高效性和特异性,未来应用前景广阔。
This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...
点击蓝字关注我们【导读】γ干扰素(IFN-γ)是激活细胞免疫反应所必需的细胞因子,在癌症免疫监视和免疫检查点阻断疗法的临床成功中发挥着至关重要的作用。2025年3月18日,中山大学的研究团队在期刊《Cell Reports》上发表了题为“AGO2 ...
Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China Key Laboratory for Biobased ...
Craig C. Mello,1960年10月18日出生于美国康涅狄格州的纽黑文,1990年获得哈佛大学生物学博士学位,1994年在美国Fred ...
本研究聚焦于人类AGO蛋白家族,通过分子动力学模拟等手段,深入探究其在RNA干扰和基因调控中的独特结构与功能,揭示其在细胞周期中的潜在作用,为相关疾病治疗提供新思路。 在生命科学领域,基因表达的精细调控一直是研究热点。人类AGO蛋白家族在RNA干扰 ...
The exosomal Argonaute 2 (AGO2) protein forms a complex with siRNAs, which is essential for siRNA-mediated gene silencing in bacteria. Even though the delivered siRNA was designed for possessing ...
Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity Shihui Chen, Carolyn Marie Phillips RNA interference pathways ...