More information: Michael Ke Wang et al, Bleeding Risks With Non–Vitamin K Oral Anticoagulants Versus Single Antiplatelet Therapy, Annals of Internal Medicine (2025). DOI: 10.7326/ANNALS-24-02132 ...

Background: The use of antiplatelet therapy in combination with oral anticoagulants remains controversial. The objective of this study was to estimate and compare the incidence of adverse and ...

Anticoagulants and antiplatelet agents pose a great risk in patients undergoing surgery. Because these products inhibit at least one, and often multiple, factors in the clotting cascade ...

and colleagues estimated the differences in bleeding risks between therapeutic-dose nonvitamin K oral anticoagulants (NOACs) and single antiplatelet therapy using data from nine randomized ...

Balancing stroke prevention and the risk of bleeding presents another challenge as we select antithrombotic therapies, whether antiplatelet agents or anticoagulants. For this, tailoring treatment ...

inadequacy of the trials using antiplatelet agents in conjunction with the standard therapies in the comprehensive management of sepsis. One of the fundamental issues in translational research in this ...

Although aspirin is routinely recommended for patients with CABG, the optimal antiplatelet regimen after CABG remains unclear. We evaluated the efficacies and risks of different antiplatelet regimens ...

Preventive measures such as initiation of anticoagulants or antiplatelet agents—some of which can be administered intravenously—are also prioritized in the hospital. Furthermore, the inpatient ...

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. During sepsis, the coagulation cascade is ...

Confounders, such as anaemia, arterial access, age, hs-CRP, diagnosis, estimated glomerular filtration (eGFR), sex, history of chronic heart failure (CHF), atrial fibrillation (AF), hypertension, ...