这项称为CUTAC的新技术专注于RNAPII结合的小片段DNA非编码序列，这些序列与它们调控的基因位于同一染色体上，使得科学家能够直接从DNA中测量基因 ...

近日，福瑞德哈金森癌症研究中心领导的研究团队分析了不同癌症类型的RNA聚合酶II（RNAPII）活性，以便了解转录增加如何促进癌症进展。他们发现，组蛋白基因上的RNAPII水平升高预示着癌症的快速复发，并与染色体丢失相对应。 全基因组范围的超转录 ...

RNAPII expression correlates with and predicts cancer aggressiveness To test their hypothesis, the researchers used CUTAC profiling to examine and map RNAPII, which transcribes DNA into precursors ...

In the study, published today in Science, the researchers discovered that the amount of a specific enzyme, RNA Polymerase II (RNAPII), found on histone genes was associated with tumor ...

Hyper-elevated levels of RNAPII on these histone genes indicate cancer over-proliferation and potentially contribute to chromosomal changes. These findings point to the use of a new genomic ...

In the study, published today in Science, the researchers discovered that the amount of a specific enzyme, RNA Polymerase II (RNAPII), found on histone genes was associated with tumor aggressiveness ...

Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers. Using a new ...