More information: Francisco M. Cruz et al, Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome, Circulation Research (2024). DOI ...

PI3K signaling pathways. Upon activation by RTK, GPCR, Integrin, and Ras, p110 loses inhibition by p85 and converts PIP2 to PIP3. PIP3 recruits AKT to the cell membrane, where AKT is activated ...

You must show flexibility towards your working hours and be ‘on call’ as part of the CID and Sergeants’ on call rota. The RSHP provides policing services on both St. Helena and Ascension Island so, ...