研究人员主要采用了动物实验、细胞培养和多种检测技术来开展研究。在动物实验方面，构建了小鼠闭合性头部损伤模型模拟重复性轻度创伤性脑损伤（r-mTBI）；细胞培养则包括对小鼠脑血管周细胞和人脑血管内皮细胞的培养；同时运用 ELISA、免疫荧光、Western blotting 等检测技术，对相关蛋白表达、细胞增殖和细胞因子分泌等进行测定。

PDGF and its receptors are implicated in tumorigenesis and angiogenesis, prompting Sebti and colleagues to design a synthetic molecule, called GFB-111, that binds to PDGF. Their new molecule has ...

Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the ...

根据弗若斯特沙利文的报告，Pro-101-1 是中国治疗烧烫伤临床开发进度最快的 PDGF 候选药物，有望成为中国首款用于该适应症的商业化的 PDGF 产品 ...

Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the Journal of Clinical Investigation, shows that the ...