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Vertex 非阿片镇痛药获批,开启 NaV1.8 靶点疼痛治疗新时代
最近获批的 Journavx 对 NaV1.1 - 1.7 和 NaV1.9 的亲和力达到亚纳摩尔级别,且选择性超过 31000 倍。 在该药物的 3 期临床试验中,2000 多名接受拇囊炎切除手术或腹部整容手术的患者,分别每 12 小时服用一次 Journavx、每 6 小时服用标准治疗药物氢可酮(一种半合成阿片 ...
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