Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

"We predict that other enzymes likely serve similar functions across the tree of life," says Darst. "The more we learn about these mechanisms, the more we deepen our understanding of how cells ...

The superfamily 1 (SF1) and SF2 enzymes are non ... they might need to function as a helicase. Hence these activities need to be regulated. Figure 3: Potential mechanisms of the regulation of ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during ... what the exact function of ARMC5 is ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Atrial fibrillation, or A-fib, is an irregular heart rhythm that increases a person's risk of stroke, heart failure and even ...

Professor Seyun Kim commented, "This study provides a vital mechanism proving that IPMK, a key enzyme in the inositol metabolism system, is a major transcriptional activator in the core gene ...