Understanding the physical basis for this activity requires knowledge ... subject with the first and second editions of Enzyme structure and mechanism by Alan Fersht. The detailed introductory ...

For some SF1 enzymes, ssDNA-translocase activity is not sufficient for helicase ... kinetic studies suggesting non-uniform translocation mechanisms. Current evidence suggests that many helicases ...

The rate of enzyme reaction can be affected by substrate concentration. As the substrate concentration increases, the enzyme reaction increases until all of the active sites are occupied by the ...

Get Instant Summarized Text (Gist) A novel mechanism has been identified that eliminates defective transcriptional elongation enzymes during gene expression. This process involves the ARMC5 ...

N orthwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

The SCAN enzyme employs this mechanism, selectively nitrosylating target proteins such as the insulin receptor and its substrates. Interestingly, the researchers discovered elevated SCAN activity ...

"Our analyses now finally provide clarity about the mechanism and ... that of a specific enzyme, glycerol-3-phosphate dehydrogenase (GPDH). This increased activity of GPDH in turn boosts the ...

This interaction facilitates the transcriptional activity of various genes ... "This study provides a vital mechanism proving that IPMK, a key enzyme in the inositol metabolism system, is a ...