他们发现，靶向转铁蛋白受体（TfR）和 CD98 重链（CD98hc）的抗体运输载体（ATV 和 ATV ）在大脑中的暴露和实质分布得到了显著增强，而且它们在细胞类型和脑区的分布上与对照 IgG 有着明显的差异。这一发现为中枢神经系统疾病的治疗带来了新的希望。 在这项 ...

Mapping the density, molecular features and energy-transformation capacity of cell organelles called mitochondria in the brain reveals region- and cell-type-specific variability that tracks with ...

A protein involved in Alzheimer’s disease progression has been linked to normal brain ageing, raising the prospect that researchers could target it to stave off age-related mental decline.

Caption In blue, the region that binds the amino acids transported in and out of the cells. The amino acid binding centre of this region is highlighted. Molecular dynamics and modeling were used ...