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TGF-β1 与 IL-3 对肥大细胞的调控机制:肝纤维化研究新突破
为探究 TGF-β1 在肥大细胞(MC)中的信号传导机制,德国研究人员对比多种 MC 进行研究,发现 TGF-β1/ALK5/SMAD2 和 IL-3/ERK1/2 通路相互作用平衡 MC 分化与增殖,为相关疾病研究提供新思路。 肥大细胞(Mast cells,MC)作为免疫系统中的重要成员,如同身体的 “预警 ...
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