With increasing numbers of short hairpin RNA (shRNA) and short interfering RNA (siRNA) libraries available to researchers along with new systematic and pooled screening approaches, RNAi screens in ...
The consequent high costs for siRNA oligonucleotides are likely to prove prohibitive for large-scale RNAi screening of primary cells. Transduction approaches place a burden on the screener in ...
A new study led by Profs. Fan Kelong and Yan Xiyun from the Institute of Biophysics of the Chinese Academy of Sciences ...
(B) An siRNA screen of 240 siRNAs against common DDR proteins in the EJ-DR assay showing the top hits phenocopying mibefradil in red, the controls siPRKDC (DNA-dependent protein kinase catalytic ...
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