Harada et al. 3 have now identified PKA as the kinase that phosphorylates serine 112 of BAD. They did this by purifying the kinase activity, which was present principally in heavy membrane ...

On page 313, Nagai et al. describe a way of visualizing phosphorylation activity of cAMP-dependent protein kinase (PKA) as it occurs in living cells. They placed a well-characterized substrate of ...

Fruit flies with genetic mutations that severely reduce sleep show enhanced performance in olfactory memory tasks, ...

Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a new study. The paradox of enhanced memory despite sleep loss could be explained ...

The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.

The paradox of enhanced memory despite sleep loss could be explained by protein kinase A (PKA) signaling in the ...

Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants ...

and PKA (cAMP-dependent protein kinase). When cAMP receives a signal from the cell's surface, it activates PKA. PKA relays ...

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a study published March 20th in ...