【导读】Wnt/β-catenin/转录因子（TCF）转录活性在结直肠癌（CRC）的发生发展中起着不可或缺的作用。然而，迄今为止，靶向该通路的药物由于不良和严重的副作用而未用于临床实践。

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Two patients exceed 14 months on treatment in Phase 2 trialof advanced ovarian cancerAllarity maintains a cash balance of $18.5 million, sufficient to advance and accelerate stenoparib’s clinical deve ...

Future research will therefore demonstrate how important the Wnt–β-catenin signalling pathway is for the self-renewal of cancer stem cells. The past two decades have seen a number of cases in ...

[miR-497 inhibits the growth and metastasis of SGC-7901 human gastric cancer anoikis resistant cells via blocking Wnt/β-catenin signaling pathway]. [Formononetin improves cognitive behavior in ...