A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly ...
To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mystery: scientists ...