In addition, vancomycin alters bacterial-cell-membrane permeability and RNA synthesis. Not for prophylaxis of endophthalmitis. Renal insufficiency. Monitor hearing, blood, renal function.

a practical approach is to monitor white blood cell (WBC) count with a differential (including absolute neutrophil count) once a week in patients who are receiving vancomycin for more than 7 days.

Mean ± S.D. vancomycin removal was 39% ± 13%. Body weight and duration of dialysis alone, blood flow rate, and dialysate flow rate were not predictive of vancomycin removal. Based on these data ...