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生物通
16 天
USP2-p53 轴调控非小细胞肺癌顺铂耐药机制新发现:开启肺癌治疗新方向
为探究非小细胞肺癌(NSCLC)顺铂耐药机制,研究人员开展关于 USP2 和铁死亡对 NSCLC 顺铂耐药影响的研究,发现 USP2 通过调控 p53 影响铁死亡进而调节顺铂耐药,为 NSCLC 治疗提供新靶点。 非小细胞肺癌(Non-small cell lung cancer,NSCLC)是一种常见的恶性肿瘤 ...
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