The market of ADME toxicology testing is critical to evaluating the safety and efficiency of new drug candidates before they are allowed VANCOUVER, BRITISH COLUMBIA, CANADA, January 16 ...

excretion and Toxicology (ADME-Tox) and efficacy in humans. In a paper by Dowden, some additional insight is provided into the reasons why failures happened. Lack of clinical efficacy was the most ...

For many years, biologists have relied on in vitro 2D cell culture models to perform preclinical ADME-Tox assays. While these models are useful, they are limited in their translatability to drug ...