The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

just over 15% of participants with gout for less than 10 years had tophaceous disease. Creatinine clearance was the major factor independently associated with early presentation with tophi.

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

参考文献[1]Danve A, Sehra ST, Neogi T. Role of diet in hyperuricemia and gout[J]. Best Pract Res Clin Rheumatol. 2021 Nov ...

an increased frequency of gouty attacks and with the presence of tophi. In the De Vera et al. study, information about these disease features was lacking, and the poor case definition of the gouty ...

Tophi are a symptom of gout. They are large, hardened masses of uric acid crystals within and around the joints. These masses can cause pain, joint deformity, and limited range of motion.

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

Gout flares among adults in the United States are significantly underreported to healthcare providers, with nearly 72% of flares either not reported or pretreated/prevented by patients, according to ...

The refractory gout market is growing because of the rising prevalence of gout brought on by aging populations and changes in ...