The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

Tophi are a symptom of gout. They are large, hardened masses of uric acid crystals within and around the joints. These masses can cause pain, joint deformity, and limited range of motion.

Among individuals with gout, 94.3% received a physician diagnosis, 99.5% had experienced a flare, and 66.0% reported having a flare in the past 12 months. Tophi were reported among 18.8% of cases.