Oral administration of the vasopressin V2-receptor antagonist tolvaptan is safe and effective for the treatment of chronic hyponatremia in the long term, according to the results of the SALTWATER ...

Expert Rev Cardiovasc Ther. 2008;6(5):601-608. The first Phase III clinical trial to study tolvaptan was the Study of Ascending Levels of Tolvaptan in Hyponatremia (SALT)-1/-2, which consisted of ...

Discover the commercial and brand names of the generic drug Tolvaptan. This indispensable guide is essential for healthcare professionals, patients, caregivers, and anyone seeking to understand ...

Tolvaptan is a vasopressin receptor antagonist. Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron.

The AVP-receptor antagonists, conivaptan, lixivaptan, and tolvaptan, are being studied for the treatment of hyponatremia. Conivaptan has been shown in clinical trials to increase free-water ...