Purpose: The pharmacology, pharmacokinetics, clinical efficacy, safety, and role of tocilizumab in rheumatoid arthritis (RA) are reviewed. Summary: Tocilizumab is a novel monoclonal antibody that ...

Treat severe or life-threatening CRS with tocilizumab or tocilizumab and corticosteroids. Neurologic toxicities, including fatal or life-threatening reactions, occurred in patients receiving ...

Standard premedications included acetaminophen, diphenhydramine, and dexamethasone. No patients received prophylactic tocilizumab, and CRS (if present) was managed in the inpatient setting. There was ...

Top coverage from the 2024 American Society of Clinical Oncology (ASCO) annual meeting included research topics in non-small ...

Physicians often treat CRS with drugs that counteract the cytokine release that causes T cells to go into overdrive. Tocilizumab, for example, has been used for years to treat CRS from ...

While the use of chimeric antigen receptor (CAR) T-cell therapy has increased rapidly, the clinical benefit seen with these ...