with the colocalization of DNA fragments and TLR9 shown in orange, activating a cell signaling pathway that promotes the removal of self-reactive B cells. But, when CXCL4 levels are elevated ...

In laboratory experiments, iSN40 was shown to interfere with the signaling pathways involved in osteoclastogenesis, particularly through the toll-like receptor 9 (TLR9) in pre-osteoclasts.

TLR9 KO animals exhibited impaired memory and learning after fear training compared ... He also noted that it would also be interesting to explore the influence and effect on this pathway in the ...