Weekly administration of prophylactic tamoxifen is much less effective than the standard daily regimen in preventing the adverse breast effects induced by bicalutamide. Bicalutamide monotherapy is ...
For patients with “good-risk” ductal carcinoma in situ (DCIS) who underwent breast- conserving surgery and did not receive radiotherapy, tamoxifen significantly decreased the risk of recurrence in the ...
Preclinical studies and early clinical trials have shown that the anticancer agent tamoxifen, a relatively selective PKC inhibitor that can cross the blood–brain barrier, exerts an antimanic ...
Wright further emphasized that knowing the risk of recurrence, with and without tamoxifen, for patients who choose to forgo radiotherapy can help patients most effectively weigh the risks and benefits ...