Review reveals nonsteroidal anti-inflammatory drugs are effective for acute pain and 5 treatments are effective for chronic pain.

UB researchers have uncovered how heat causes a critical receptor protein within cells to unfold and relay pain.

Only around one in ten non-surgical and non-interventional treatments for lower back pain are effective, a research study has ...

It's all about a chemical compound in peppers called capsaicin. Capsaicin binds to pain receptors on our nerves called TRPV1. Normally, it reacts to heat by sending warning signals to the brain.

Further experiments revealed that scratching triggers a neuroimmune pathway that starts from TRPV1-expressing neurons that release substance P, a neuropeptide released by pain-sensing neurons ...

Binshtok et al. theorized that it could be possible to exploit the transient receptor potential vanilloid type 1 (TRPV1) channel, which is sensitive to noxious heat and capsaicin, to selectively ...