On the basis of their genetic similarity to the Toll signaling pathway in Drosophila, mammalian Toll-like receptors (TLRs) have been identified. By now, nine transmembrane proteins in the TLR ...

Jean-Laurent Casanova and colleagues report in Science a Toll-like receptor 3 (TLR3) deficiency in two children with herpes simplex virus type 1 (HSV1) encephalitis (HSE), and identify autosomal ...

Moon-Hyeong Seo, screened over 190,000 peptide candidates to find molecules that could target specific inflammatory proteins called Toll-like receptors (TLRs). These proteins play a key role in ...

McEwen Mining Acquires Timberline To 'Unlock Synergies' In Nevada Gold Operations McEwen Mining acquires Timberline Resources for $18.8 million in a stock-for-stock transaction, driven by ...

Discover how leveraging TLR7/8 agonists in combination with systemic IFN-I represents a promising strategy for treating melanoma.

Timberline Resources (OTCQB:TLRS) +132.6% in Tuesday's trading after McEwen Mining (NYSE:MUX) agreed to acquire the company in a deal valued at $18.8M, which McEwen (MUX) said will augment its ...