Jiangsu Hengrui Medicine Co. Ltd. and Shanghai Hengrui Pharmaceutical Co. Ltd. have disclosed Toll-like receptor 7 (TLR7) and/or TLR8 and/or TLR9 antagonists reported to be useful for the treatment of ...
Research published in Nature indicates that persistent signaling downstream of Toll-like receptor (TLR)-7 and TLR9 in plasmacytoid dentritic cells (pDCs) might explain why glucocorticoids are less ...
News Medical on MSN2mon
Complex interactions between nucleic acid sensors and enzymes in immune cells explainedA denosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to ...
TLR7 and TLR9 are also thought to be involved in B-cell-mediated production of autoantibodies specific to nucleic acids, thereby triggering and then promoting SLE. Barrat et al. have described ...
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