Immuno-oncology (IO) has transformed cancer care ... led to the discovery of novel multi-specific antibodies that target TCR variable beta (Vβ)-chain variants—powerfully activating the right ...
Which is best suited for immuno-oncology? Cancer research and drug ... Checkpoint inhibitors, CAR-T cells, modified TCR T cells, and vaccines in various forms are now the frontier of oncology ...
Immunocore has secured a piece of biotech industry history, becoming the first company to get an FDA approval for a cancer therapeutic based on T cell receptor (TCR) technology. The US regulator ...
Overall, equivalent specificity, safety, and functionality of UniTope-modified rTCRs, compared with unmodified rTCRs, demonstrates the versatility of the UniTope & TraCR System as a high precision ...