Johns Hopkins Medicine laboratory scientists say they have developed a potential new way to treat a variety of rare genetic ...

The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known to play a key role in supporting the development of synapses and ...

Mill Valley, CA – February 11, 2025 – The SynGAP Research Fund 501(c)(3) dba Cure SYNGAP1 proudly announces the release of its inaugural Impact Report, a transparent and celebratory reporting ...

As the SynGAP protein supports the development and strengthening of synapses, enabling healthy communication between neurons, the lower production of this protein can adversely impact brain function.

The development could pave the way for therapies for rare disorders including some forms of cancer. It also holds potential for therapies to treat immune system and neurodegenerative disorders, ...

Such disorders, although rare, include some forms of cancer, and immune system and neurodegenerative disorders, including SYNGAP deficiency, which results in learning disabilities and autism ...