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双等位基因活性的胚胎增强子通过等位基因特异性构象指示GNAS印记
STX16微缺失仅在母体等位基因上引起假甲状旁腺功能低下- 1b型。在这里,作者表明等位基因特异性致病性反映了决定GNAS印迹的双等位基因活性增强子的不同构象。 双等位基因活性胚胎增强子通过等位基因特异性构象决定 GNAS 印记 在生命科学领域,基因组印记是 ...
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