The peripheral endoplasmic reticulum (ER) forms a continuous ... Investigating how the unique structure of the ER arises and supports its function is critical to developing a mechanistic ...

New research, published recently in Proceedings of the National Academy of Sciences, uncovers the unique dynamics governing ...

COPII works at the endoplasmic reticulum and clathrin acts at the plasma membrane. Lee and Goldberg now determine the structure of a COPI subcomplex and find that it shares key features of both ...

The endoplasmic reticulum (ER) is a crucial organelle present in all eukaryotic cells, including human cells. The ER plays a ...

The structure of CRT suggested that it has ... is considered a characteristic quality control process of the endoplasmic reticulum), and ii) CRT regulates intracellular calcium levels, acting ...

The Jokitalo group studies structure-function interplay of organelles in mammalian cells. Our main model organelle is the endoplasmic reticulum. We employ a wide range of basic biological techniques ...

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...

Researchers from Stanford University and LMU have uncovered how cells renew their endoplasmic reticulum’s protein factories. One of the essential functions of life is the cell’s synthesis of ...