mail.ncku.edu.tw Background: In the rat brain, heat-stroke-induced damage to cerebral neurons is attenuated through heat-shock-induced overexpression of heat-shock protein 72 (HSP72). Objective: To ...

More information: Barbara Klein et al, Modified human mesenchymal stromal/stem cells restore cortical excitability after focal ischemic stroke in rats, Molecular Therapy (2024). DOI: 10.1016/j ...

While most stroke treatments must be administered in the immediate hours after a stroke to have a benefit, the cell therapy was effective in rats even when given one month later.