Spironolactone was initiated at a dose of 25 mg daily at the first ambulatory blood pressure monitoring and titrated to 50 mg or 100 mg daily after office-based assessment of blood pressure at ...

25–50 mg daily for 1 year. Five patients taking spironolactone and one patient on placebo developed hyperkalemia within 2–12 weeks of initiation of study medication and were excluded.

The spironolactone report counted the 7,062 patients randomized to spironolactone 25 mg once daily versus placebo within 72 hours following PCI. Patients logged a median 3 years of follow-up.

However, they might recommend starting with 25 mg a day and slowly increasing your dose to reduce your risk of side effects. Spironolactone sometimes causes drowsiness, so it’s best to take it ...

CHICAGO -- Treatment with the potassium binder sodium zirconium cyclosilicate (SZC; Lokelma) stabilized potassium levels among patients with heart failure with reduced ejection fraction (HFrEF ...