2). ExoPTEN has been tested as an intra-nasally administered formulation in an extreme rat model of acute SCI: complete transection of the spinal cord resulting in paraplegia. In an internal ...
A 9-month-old adult female Sprague-Dawley rat from a colony of spinally transected rats presented 10 days after spinal cord transection surgery with a 2-day history of abdominal distention.
The rat, once paralysed with a completely severed spinal cord, had weeks earlier undergone pioneering surgery, as part of research headed by Technion and Tel Aviv University. Professor Shulamit ...